Internal Medicine News - Quick antidepressant effect seen with escitalopram/bupropion mix.(Psychiatry)

BOCA RATON, FLA. — A combination of escitalopram and bupropion might produce early remission in as many as one-third of patients with unipolar depression, according to a pilot study presented at a meeting of the New Clinical Drug Evaluation Unit sponsored by the National Institute of Mental Health.

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However, the faster onset of action and increased remission rate observed with this combination, compared with monotherapy, come at a cost of increased adverse events. “In my mind, the adverse events were manageable in most patients,” said Jonathan W. Stewart, M.D., a …

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