Internal Medicine News - With or without ADHD: bupropion may help reduce nicotine dependence in teens
Adolescents with nicotine dependence may benefit from bupropion, whether or not they have comorbid attention-deficit hyperactivity disorder, said Dr. Himanshu P. Upadhyaya and colleagues at the Medical University of South Carolina, Charleston.
Bupropion slow release (SR) has been shown to be effective against nicotine dependence in adults, but no prior studies had tested its effectiveness on adolescents (J. Am. Acad. Child Adolesc. Psychiatry 43[2]:199-205, 2004).
A pilot study included 16 adolescents aged 12-19 years who smoked at least five cigarettes per day. Fifteen teens received 300 mg/day, and one received 150 mg/day due to gastrointestinal side effects. In addition, all patients received two counseling sessions about smoking cessation.
Related Results
Bupropion and schizophreniaBupropion for smokersAbuse of bupropionBupropion Benefits Smoking CessationBupropion Or Patch For Smoking Cessation?
After 4 weeks, cigarette cravings decreased significantly, from a mean score of 4.35 to 2.33 as measured by the Questionnaire for Smoking Urges-Brief (QSU-B).
The study was funded in part by a grant from GlaxoSmithKline.
COPYRIGHT 2004 International Medical News Group
COPYRIGHT 2008 Gale, Cengage Learning
